The invention relates to a lubricating oil anticreaming agent, and a preparation method and application thereof. Trimellitic anhydride, epoxy chloropropane and DFI (2,2-difluoro-1,3-dimethyl imidazolone) are selected as raw materials for preparing a polyether lubricating oil anticreaming agent containing a fluorine group. After the anticreaming agent provided by the invention is used in oil film bearing oil, the anticreaming performance of a lubricating oil product can be obviously improved; the defects of great consumption and poor matching performance with other lubricating oil additive ingredients of the existing conventional anticreaming agent in the prior art are overcome.