The invention provides a health medicinal liquor for invigorating spleen and eliminating dampness and a preparation method thereof. The medicinal liquor comprises Baijiu and traditional Chinese medicines, wherein the traditional Chinese medicines comprise the following components: white hyacinth bean, paniculate swallowwort root, medicated leaven, radix aucklandiae, bighead atractylodes rhizome, sea-buckthorn, rhizoma atractylodis, rice sprout, dried orange peel, malt, gynostemma pentaphylla, caulis sinomenii, alpinia katsumadai hayata, amomum kravanh, herba eupatorii, flos mangnolia officinalis and villous amomum pericarp. The preparation method comprises the following steps: weighing the raw materials in parts by weight, cleaning, drying and grinding the raw materials in sequence, and uniformly mixing the raw materials; putting the mixed traditional Chinese medicine raw materials in a percolator, soaking the mixed traditional Chinese medicine raw materials for 48-72 hours by taking Baijiu as a solvent so as to percolate slowly, collecting the original percolated liquid, continuing the percolating, collecting the percolated liquid, concentrating the percolated liquid, uniformly mixing the concentrated percolated liquid with the original percolated liquid, adjusting the gross through Baijiu, leaving to stand for 48 hours or above, and carrying out filtration and split charging to obtain the health medicinal liquor. The traditional Chinese medicine components have the effects of invigorating spleen and eliminating dampness; through coordination between the traditional Chinese medicines, the effects of eliminating heat, warming spleen, discharging fire and promoting appetite are sufficiently strengthened, the functions of dissolving turbidity, lowering lipid and lowering heat are achieved, and no side effects is caused.