The invention discloses a crab-meal silico-calcium stock solution. The crab-meal silico-calcium stock solution is characterized by being prepared through the following steps: (1) removing flesh from shrimp and crab shells; (2) crushing the shrimp and crab shells until the grain size of the shrimp and crab shell powder is at least 200 meshes, then, uniformly mixing the powder with a blended acid solution, carrying out stirring, and then, carrying out soaking for 20 to 30 hours while maintaining the temperature of 45 DEG C to 55 DEG C; and (3) separating solid from liquid, thereby obtaining a fluid part, i.e., the crab-meal silico-calcium stock solution. The invention also discloses an application of the crab-meal silico-calcium stock solution. The crab-meal silico-calcium stock solution and the application thereof have the advantages and positive effects that the crab-meal silico-calcium stock solution prepared by the preparation method disclosed by the invention is high in silico-calcium absorption ratio, low in preparation cost and simple in preparation process, and pollutants are not discharged and not generated.