The invention relates to a rubber and plastic folding water stop strip type one-way automatic drain valve. The rubber and plastic folding water stop strip type one-way automatic drain valve is characterized by consisting of a hole hourglass type folding water stop strip (1), a top plate (2), a first outer casing pipe (4), an inner casing pipe (5), a second outer casing pipe (6) and quartz sand (7), wherein water draining holes (3) are formed in the hole hourglass type folding water stop strip (1); the upper part of the hole hourglass type folding water stop strip (1) and the top plate (2) are seamlessly connected by adhesive; the lower part of the hole hourglass type folding water stop strip (1) is connected with the first outer casing pipe (4) through a clamping groove (11); the upper end and the lower end of the inner casing pipe (5) are separately inserted into the first outer casing pipe (4) and the second outer casing pipe (6); the quartz sand (7) is placed inside the second outer casing pipe (6); and water inlet holes (8) are formed in the bottom of the second outer casing pipe. The rubber and plastic folding water stop strip type one-way automatic drain valve disclosed by the invention adapts to any water quality and can automatically drain water without manual operation, so that time and labor are saved.