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发明授权
CN105732684B 一种制备芳基硼酸新戊二醇酯的方法 有权 转让

一种制备芳基硼酸新戊二醇酯的方法
摘要：
本发明公开了一种制备芳基硼酸新戊二醇酯的方法，以化学式为Ni[P(OR1)3][(R2NCH2CH2NR2)C]X2的混配型镍(II)配合物为催化剂、在甲醇钾的存在下高效地催化苯基氯代物与联硼酸新戊二醇酯的交叉偶联反应以制备芳基硼酸新戊二醇酯，这是以亚磷酸酯和氮杂环卡宾作为辅助配体的混配型镍(II)配合物催化这类交叉偶联反应的第一例。
摘要（英）：

The invention discloses a method for preparing arylboronic acid neopentyl glycol ester.The method includes the steps that a mixed-type nickel (II) complex with Ni(P(OR1)3)((R2NCH2CH2NR2)C)X2 as the chemical formula serves as a catalyst, and a cross coupling reaction of phenyl chlorine substitutes and bis(neopentyl glycolato) diboron is efficiently catalyzed in potassium methoxide to prepare the arylboronic acid neopentyl glycol ester.The method is the first case that the mixed-type nickel (II) complex catalyzes the cross coupling reaction with phosphite ester and n-heterocyclic carbine as auxiliary ligands.

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