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发明公开
CN105646792A 含扑热息痛结构的聚甲基聚乙二醇丙烯酸酯血液相容性涂层的制备 无效 - 撤回

含扑热息痛结构的聚甲基聚乙二醇丙烯酸酯血液相容性涂层的制备
摘要：
含扑热息痛结构的聚甲基聚乙二醇丙烯酸酯血液相容性涂层的制备其特征在于将4-硝酸酯-对丙烯酰胺苯基丁酸酯(NAPB)及其类似物、丙烯酸甲酯(或类似物)、甲基聚乙二醇丙烯酸酯(及其衍生物)混合。其中APBN质量百分比为1-20％，丙烯酸甲酯(及其类似物)质量百分比为50％-85％，甲基聚乙二醇丙烯酸酯(及其衍生物)的质量百分比为10-30％。在氮气保护下自由基聚合。反应温度为20～90℃；反应时间1～20小时用石油醚和四氢呋喃将生成的聚合产物反复沉淀、溶解。最后真空干燥。
摘要（英）：

The invention relates to preparation of a polymethyl polyethylene glycol acrylate blood compatible coating containing paracetamol structure. The preparation method is characterized by mixing of NAPB and its analogue, methyl acrylate (or analogue), methyl polyethylene glycol acrylate (and its derivative). Specifically, the mass percentage of APBN is 1-20%, the mass percentage of methyl acrylate (and its analogue) is 50%-85%, and the mass percentage of methyl polyethylene glycol acrylate (and its derivative) is 10-30%. Free radical polymerization is carried out under nitrogen protection, the reaction temperature is 20-90DEG C, the reaction time is 1-20h, the generated polymerization product is repeatedly precipitated and dissolved by petroleum ether and tetrahydrofuran, and finally vacuum drying is performed.

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