The invention discloses a white-light large-power LED drive circuit. Selection of a die of a white-light large-power LED lamp can reduce design difficulty and cost; light intensity and power of the white-light large-power LED lamp can solve the problem of small power of the LED lamp; a power-factor correction module adopts a continuous mode, so that design of a filter circuit can be simplified; working range of the power-factor correction module can enlarge power use range; parameters of voltage, current and temperature are monitored by a protection module, so that the circuit can be fully protected, and the service life can be prolonged; and the LED drive circuit has very high application value.