The invention discloses an efficient labware cleaning device, and aims to provide the efficient labware cleaning device with low labor intensity, high cleaning efficient and no potential safety hazard and capable of effectively guaranteeing the labware cleaning quality. The efficient labware cleaning device comprises a frame, a cleaning barrel rotationally arranged on the frame through a vertical shaft rod, a netty separation layer arranged at the lower part of the cleaning barrel, and a rotary actuation mechanism for driving the cleaning barrel to rotate; and multiple stirring rods parallel to the vertical shaft rod are arranged in the cleaning barrel.