The invention discloses nicked-based ternary intermediate alloy containing high-melting-point components and a preparation method of the nickel-based ternary intermediate alloy. Ni is used as a base body, high-melting-point metal including Ru, Mo, Ta and Re is added into Ni, the ternary intermediate alloy is formed by Ni and any two kinds of the high-melting-point metal added into Ni, and one of the any two kinds of the high-melting-point metal added into Ni is Ta. The invention further discloses a preparation method of the nicked-based ternary intermediate alloy containing the high-melting-point components. The melting point of the intermediate alloy prepared through the method is lower than 1600 DEG C and is far lower than that of refractory alloy elements contained in nicked-based high-temperature alloy, so that in the process of smelting master alloy, the required heating temperature is obviously decreased, the required heating time is obviously shortened, and meanwhile the burning loss of low-melting-point metal is reduced.