The present invention discloses a method for producing 2-ethylhexyl alcohol sulfate salt. The method is as below: injecting different inlet 2-ethylhexyl alcohol and a liquid sulfonating agent into a micro-reactor from different inlets of the micro-reactor, mixing and conducting a sulfonation reaction; controlling the reaction temperature at 5-50 DEG C, staying the reaction products in the micro-reactor for 0.5 milliseconds to 5 seconds, and then sending the reaction products into a micro-mixer connected with the micro-reactor to neutralize with a neutralizing agent, and aging for 0-30 min after neutralization, so as to obtain a transparent light yellow 2-ethylhexyl alcohol sulfate salt liquid. The method uses liquid-liquid phase reaction for synthesis of 2-ethylhexyl alcohol sulfate salt, not only obtains a high yield of 100%, but also does not produce any waste gas and waste requiring subsequent treatment. The method simplifies the production process, and improves the production effectiveness.