The invention discloses a squeeze osmosis packaging film and a production process thereof. The squeeze osmosis packaging film is divided into an outer-layer thin film, a middle-layer thin film and an inner-layer thin film, wherein linear low density polyethylene and low density polyethylene are adopted as raw materials for the outer-layer thin film; linear low density polyethylene and low density polyethylene are adopted as raw materials for the middle-layer thin film; metallocene polyethylene, EVA and a slipping agent are adopted as raw materials for the inner-layer thin layer. After being subjected to heat sealing with heat sealing strength of 1 to 5N/5mm, the squeeze osmosis packaging film has the advantages of high heat sealing performance, high sealing stability, relatively low heat sealing strength and the like.