The invention discloses a shape memory type high-elasticity activity nano-fiber stent and application thereof. The shape memory type high-elasticity activity nano-fiber stent is manufactured by introducing biological activity components (laminin, heparin, CD34+, VEGF and the like) into degradable linear elasticity polyester PCT with a shape memory effect through an electrostatic spinning technology; the molecular weight of the linear elasticity polyester PCT is 50000-400000, and the percentage composition of functionality caprolactone monomers, containing side cyclic ether substitutes, in a copolyester is 5-50%. The shape memory type high-elasticity activity nano-fiber stent is a high-activity nano-fiber stent with human body biomechanics elasticity, is a three-dimensional degradable tissue engineering stent which can provide an ideal biomechanics environment and an ideal biological activity microenvironment for cell growth, and is expected to be widely applied to regeneration and repair of elastic human body tissue such as blood vessels, cardiac muscles, nerves, skin, tendon, heart and the like.