The invention provides an oil and gas well data comprehensive acquiring and processing device comprising a main board, a single-chip microcomputer, an ARM processor, a WiFi module, and multiple first Zigbee modules. The multiple first Zigbee modules correspond to multiple wireless sensors respectively and may communicate with the corresponding wireless sensors via a Zigbee protocol, and acquire oil and gas well data measured by the corresponding wireless sensors. The single-chip microcomputer is soldered on the main board and is connected with the ARM processor and the WiFi module. When being connected with the first Zigbee modules, the single-chip microcomputer receive the oil and gas well data sent by the first Zigbee modules, transmits to the ARM processor the oil and gas well data to be computed, receives processed oil and gas well data returned by the ARM processor, and then sends the processed oil and gas well data to the WiFi module. The WiFi module sends the processed oil and gas well data to a mobile device by means of WiFi wireless communication technology. The oil and gas well data comprehensive acquiring and processing device may obviously increase efficiency of onsite acquiring, checking, and processing oil and gas well data at an oil field.