The invention discloses a wet airflow crushing dispersion method of nanometer calcium carbonate. The method comprises the following steps: carrying out dry crushing on calcium carbonate ores to form powder with the fineness of 400 meshes, mixing the powder with water to prepare a slurry, adjusting the viscosity of the slurry, grinding the adjusted slurry through a wet medium stirring crusher, introducing airflow through a wet airflow crushing dispersion machine, carrying out high-speed rotating crushing dispersion, carrying out surface active treatment, drying the obtained material, and grading the dried material to obtain a fine and stable high-quality product. Airflow dispersion is introduced in the airflow crushing dispersion method of nanometer calcium carbonate, and high pressure and high speed movement of particles forms high impact intensity and shearing stress in a specially produced crushing chamber, so liquid drops are atomized, particles are broken, the fineness of the further crushed particles reaches nanometer level, crushing and dispersion are simultaneously carried out, and the effects are substantial.