The embodiment of the invention provides a dead-time compensation method and device of an inverter. The dead-time compensation method of the inverter comprises the following steps of acquiring AC current output from the inverter; determining compensation voltage according to the AC current; carrying out pulse modulation and generating a pulse modulation signal according to the compensation voltage and fundamental wave output voltage of the inverter; and carrying out dead-time compensation control on the inverter according to the pulse modulation signal. Through the dead-time compensation method and device of the inverter, provided by the invention, the dead-time voltage is accurately and dynamically compensated, the distortion probability of the output current of the inverter is reduced, and the electric energy quality is enhanced.