The invention discloses a high-voltage isolation switch. The high-voltage isolation switch comprises a dynamic arc contact and a static arc contact, wherein the dynamic arc contact and/or the static arc contact is wound with an arc suppression coil used for generating a magnetic field during tripping. In the current conversion process of an isolation switch on-off bus, an electric arc is generated between the arc suppression coil and the dynamic arc contact or the static arc contact, and an electric arc current enters the arc suppression coil to form the magnetic field. The electric arc starts rotating under the action of the magnetic field, is cooled and lengthened by pulling, and finally is safely extinguished at a current zero-crossing point. According to the isolation switch, the current conversion capability of the isolation switch on-off bus is improved and the electric arc ablation degree of the contact is reduced.