The present invention provides a modeling and optimization method for a piston compressor vibration isolation system. The method comprises the following steps: optimizing and obtaining a three-freedom-degree vibration isolation model; establishing a vibration equation; calculating a vibration force transfer rate; and optimizing a parameter of the vibration isolation system, so that vibration and noise reduction can be carried out on the piston compressor. The present invention establishes a mathematical model on a proposed kinetic model, solves an optimum value by using an optimization method-complex method, and acquires an ideal needed stiffness of a spring group, thereby achieving the aim of reducing noise and vibration of the compressor.