A rock filled fracture permeability test method considering multi-factor affect belongs to the rock filled fracture permeability test method and apparatus. The method is as below: preparing a of standard sample containing prefabricated axially-through filled fractures, wherein the geometry parameters and filling cementation features of the fracture can be adjusted. The apparatus includes a fracture normal constraint board, a rigid connecting rod and a nut. A tape and a heat shrink tubing are used to seal the an upper pressure head, a filling cracks and a porous disc and the samples containing filled fractures; the upper pressure head is provided with a side outlet; the sealed sample is entirely placed into a fracture normal compression loading device, a torque wrench is used for loading and fixing, and the torque value is changed to adjust the compactness of the filler; and a fracture seepage test is conducted on a test machine, the piston speed is selected, the amount of water outlet is recorded, and a steady-state method equation is used to calculate the permeability. The apparatus has the characteristics of simple structure, easy operation, low cost and high accuracy, and has broad application prospects in the research of rock filled fracture seepage test.