The invention discloses a manufacture method of a connecting rod of an air compressor and belongs to the technical field of low-pressure manufacture process. The method is used for solving the problems of conventional manufacture processes that production cost is relatively high, abrasion resistance is relatively poor, and use requirements of new-structure aluminum connecting rod without a bearing bush and a shaft sleeve are hard to meet. The method comprises the following steps: 1, firstly designing a reasonable pouring system and manufacturing a low-pressure casting sand mold according to the connecting rod of the air compressor; 2, smelting alloy b adopting a melt processing technique; 3, carrying out low-pressure casting on the alloy to obtain a required connecting rod. According to the invention, the original production technique of the connecting rod can be improved, a technique method for the aluminum alloy connecting rod simple in technique and light in weight and high in strength can be provided, thus having great economic significance.