The invention relates to a mobile phone with built-in wheels and a driving system of the built-in wheels. The mobile phone comprises a display screen, a motherboard circuit, a USB interface circuit, a USB interface power source line, a USB interface data line, a power source circuit and a battery; and the mobile phone further comprises a wheel driving system, a first second wheel, a second wheel, a third wheel and a fourth wheel. According to the mobile phone of the invention adopted, the moving trajectory of the mobile phone can be set arbitrarily through touching the display screen, and the wheels can be driven through the set moving trajectory, so that the mobile phone can be enabled to move, and the functions of an intelligent toy can be realized, for example, arbitrarily set motion trajectory charts, data and the like can be displayed on the display screen or stored in the motherboard circuit of the mobile phone, so that the mobile phone can realize the functions of a programmable intelligent toy car according to requirements, and therefore, entertainment quality can be improved, and a user will be satisfied and interested, the application range of the function of the mobile phone can be expanded.