The invention relates to a method for preparing 7-epi-taxane compounds from 7-beta-hydroxy taxane compounds. The method comprises the step of converting 7-beta-hydroxy taxane compounds into 7-epi-taxane compounds in the solvent S under the existence of a catalyst M, wherein the solvent S is one or more selected from a polar aprotic solvent, a polar protonic solvent and a nonpolar solvent; the catalyst M is one or more selected from silver, copper, iron, silver salt, copper salt, ferric salt, silver oxide, silver sulfide, copper oxide, copper sulfide, ferric oxides and ferric sulfide. The method has the advantages of high simpleness, efficiency, economy and environmental friendliness.