The invention relates to a treatment method for high-concentration fluorine-containing wastewater in the fluorine chemical industry, and belongs to the field of wastewater. The method includes the steps that CaCl2 is added into the wastewater, one part of calcium fluoride sediment is generated under the alkaline condition, and water molecules conglobated around calcium fluoride are absorbed by introducing Fe3+ ions in the precipitation process of calcium fluoride; meanwhile, plant mixed leach liquor is introduced, water molecules around fluorine ions are absorbed, the water molecules and the fluorine ions are organically combined and cannot be conglobated during precipitation of the calcium fluoride, crystals are gradually crystallized and increased, the crystallization rate is increased, the crystallization efficiency is improved, the calcium fluoride is quickly precipitated and flocculated into large crystal nuclei, and thus sedimentation is facilitated. The method has the advantages that the treatment efficiency is improved, the fluorine content of the treated wastewater is lowered to 4-5 mg/L from 70-80 mg/L, and the national wastewater discharge standard is reached; meanwhile, the treatment process is simple, consumption of chemicals is reduced, and treatment cost is lowered.