The invention discloses an active noise reduction system and a method. The active noise reduction system comprises a sound acquisition device, a motion signal acquisition device, a controller and a sound playing device, wherein the sound acquisition device is used for acquiring error noise signals in the environment; the motion signal acquisition device is used for acquiring motion signals at a specific position on a device generating primary noise signals and related to the primary noise signals; the controller is used for using a support vector machine to generate reference noise signals according to the motion signals, adjust the reference noise signals according to the error noise signals and then generate secondary noise signals; and the sound playing device is used for playing the secondary noise signals in the environment. The error noise signals are generated by overlapping the primary noise signals and the secondary noise signals. In the above active noise reduction system and the method, the support vector machine is used for predicting noise in the environment in real time. The generated reference noise signals have real-time performance and accuracy, and the noise reduction effects are improved significantly.