The invention discloses a mounting method of complex well trajectory centralizers. The method includes: using a cubic spline interpolation calculation method, and using a preset interpolation step length to perform interpolation calculation on the trajectory measured data of a well section so as to obtain the well dip angles and azimuth angles of positions, at optional well depths, of the well section; determining the configuration intervals of the centralizers on the basis of the well dip angles and azimuth angles; determining the mounting positions and number of the centralizers on a sucker rod. By the method, the use number of the centralizers can be reduced to the maximum extent, an oil pipe and the sucker rod are sufficiently protected, oil well pump inspection cycle is prolonged effectively, and operation cost is lowered.