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发明公开
CN105228646A 基于酵母的脊索瘤免疫疗法 有权

基于酵母的脊索瘤免疫疗法
摘要：
本发明的一个实施方案涉及治疗具有脊索瘤的个体中的脊索瘤的方法。该方法包括对具有脊索瘤的个体施用免疫治疗性组合物的步骤，所述免疫治疗性组合物包含：(a)酵母媒介物；和(b)包含至少一种畸形短尾抗原的癌症抗原。本发明的另一个实施方案涉及免疫治疗性组合物用于具有脊索瘤的个体中的脊索瘤的方法，所述免疫治疗性组合物包含酵母媒介物和包含至少一种畸形短尾抗原的癌症抗原。本发明的又一个实施方案涉及包含酵母媒介物的免疫治疗性组合物的用途。
摘要（英）：

One embodiment of the invention relates to a method to treat chordoma in an individual who has chordoma. The method includes the step of administering to an individual who has chordoma, an immunotherapeutic composition comprising: (a) a yeast vehicle; and (b) a cancer antigen comprising at least one Brachyury antigen. Another embodiment of the invention relates to the use of an immunotherapeutic composition comprising a yeast vehicle and a cancer antigen comprising at least one Brachyury antigen to chordoma in an individual who has chordoma. Yet another embodiment of the invention relates to the use an immunotherapeutic composition comprising a yeast vehicle.

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