The invention discloses a hoisting and flushing protective device for acid alkaline equipment. The hoisting and flushing protective device comprises a sleeve protective hood, a sealed hoisting cover and a guide bottom hood, wherein the sleeve protective hood is a tubular structure and provided with a multidirectional flushing slot in top; the sealed hoisting sleeve is arranged in an inner cavity of the sleeve protective hood in a sleeving mode, and is connected with a hoisting clamping cover device or a butt-joint clamping cover device; a hoisting lifting ring and a butt-joint lifting ring are respectively arranged on the top and the bottom of the sealed hoisting cover; the guide bottom hood is a hose type structure, and a clamping sleeve tube opening and an opening-closing tube opening are respectively formed in the top end and the bottom end of the guide bottom hood. According to the embodiment, equipment with a toxic gas or a corrosive liquid is placed in the inner cavity of the sleeve protective hood for sealing and hoisting, so that an accident that a maintenance worker is poisoned and burnet by the corrosive liquid is avoided; and sewage of the flushing equipment is collected into a container by virtue of the guide bottom hood, purified and then exhausted, so that the environment being polluted by sewage is avoided. The hoisting and flushing protective device for acid alkaline equipment is reasonable in structure, convenient in use and capable of improving the working safety of the maintenance worker.