The invention discloses a pistol-type circumcision anastomat with a safety catch; the circumcision anastomat comprises a glans penis base, a regulating rod, a regulating handle, a cylindrical knife, a suturing nail ejecting drum, a hollow ejector rod, a nail cartridge ring and suturing nails arranged inside the nail cartridge ring, wherein the cylindrical knife is sleeved inside the suturing nail ejecting drum in a mode of mounting coaxially; the circumcision anastomat further comprises a pistol body and a trigger transmission mechanism; the pistol body is composed of a tubular body part, a main shell part and a handle part; the trigger transmission mechanism is composed of a trigger, a transmission piece, a transmission arm, a swing arm, a sliding block and a reset spring; the safety catch is arranged on the trigger; and the safety catch comprises a hinge shaft, a supporting rod, a button, a sliding block, a reset spring and a guide groove. The circumcision anastomat disclosed by the invention, by adding the safety catch and by designing the safety catch, is safer and more convenient in operation, and the circumcision anastomat fully manifests the design concept of being user-friendly.