The invention provides a method for removal of aflatoxin from peanut skin. The method includes the steps of: (A) pre-treating peanut skin, then conducting ultrasonic extraction to obtain an extracted liquid, and subjecting the extracted liquid to filtration and pressure reduced distillation to obtain a concentrated solution; (B) adding water into the concentrated solution to perform dilution, then passing the diluted concentrated solution through macroporous resin to conduct chromatography adsorption separation, controlling the speed of the solution flowing through the macroporous resin at 0.3-0.5mL/min, then conduction elution with an ethanol water solution with a volume percentage concentration of 3-40%, controlling the elution flow speed at 3-5mL/min, collecting the eluent and performing evaporation and concentration. The method for removal of aflatoxin from peanut skin provided by the invention has the characteristics of mild operation conditions and low cost, can ensure the quality of the extracted proantho cyanidins and also can well remove the aflatoxin therein, enhances the follow-up application food safety of proantho cyanidins extracted from peanut skin, causes no hazard to human health, and is very suitable for extensive application and promotion.