The invention relates to production equipment and a production process of LED lamp strips based on silica gel co-extrusion technology. The production equipment comprises an equipment body which is provided with a material discharging device, a line arrangement device, an extruding device, a molding device, a hot air vulcanization tunnel furnace and a material collecting device which are connected in sequence; the extruding device comprises a controller and a driving device, an extruding mold head and a coloring mold head which are connected with the controller. The production process of the LED lamp strips comprises the steps of preparing materials, mixing, slitting, arranging, extruding and shaping, adjusting, molding again, discharging and carrying out aftertreatment. According to the production equipment and the production process, LED lamp tubes and LED silica gel lamp strips are simultaneously extruded in the high-temperature environment without manual gel injection or manual pipe penetration, and the produced lamp strips have the effects of preventing high and low temperatures and water soaking.