The invention relates to a sand prevention mode selection method, which comprises the following steps of: using a full-dimension simulation device for performing sand discharge simulation experiment; respectively determining the boundary control points of four sand prevention modes (an open hole slotted screen pipe sand prevention mode, an open hole high-quality screen pipe sand prevention mode, a gravel filling and slotted or wire wounded sand prevention mode and a gravel filling and high-quality screen pipe sand prevention mode) about the montmorillonite absolute content; sequentially determining the boundary control points of the four sand prevention modes about the median grain diameter d<50>, the Sc value, the Uc value and the fine grain content; sorting the boundary control points of the five factors of the four sand prevention modes, and making a radar map; and (7) connecting five actually measured stratum data in the radar map into a line, wherein a region defined by the connecting line is the sand prevention mode expected to be selected. The method has the advantage that the reasonable sand prevention mode is conveniently and fast selected on the premise of integrally considering the five factors including the d<50>, the fine grain content, the Uc value, the Sc value and the montmorillonite absolute content.