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发明授权
CN104884067B 包含S-腺苷甲硫氨酸及没食子酸酯的组合物 有权 转让

包含S-腺苷甲硫氨酸及没食子酸酯的组合物
摘要：
本发明提供包含S‑腺苷‑L‑甲硫氨酸（“SAM‑e”或“SAMe”）及一种或多种没食子酸酯的组合物和制剂。本发明还提供用于改善SAMe的递送的方法。本发明所提供的组合物和制剂增加SAMe血浆浓度和曲线下面积（AUC）值。本发明还提供通过施用包含外源性SAMe及一种或多种没食子酸酯的组合物或制剂来治疗受试者的疾病或病症的方法。
摘要（英）：

Provided herein are compositions and formulations comprising S-adenosyl-Lmethionine ("SAM-e" or "SAMe") and one or more gallic acid esters. Also provided herein are methods for improving the delivery of SAMe. Compositions and formulations provided herein increase SAMEe plasma concentrations and area under the curve (AUC) values. Also provided herein are methods of treating a disease or disorder in a subject by administering compositions or formulations compromising exogenous SAMe and one or more gallic acid esters.

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