The invention discloses a multi-plant composition and an extract thereof as well as a preparation method and application of a microcapsule. The multi-plant composition comprises the following six natural plants folium ginkgo, mother chrysanthemum, honeysuckle, liquorice, dandelion and oat as natural plant active components at the mass ratio of (0.5-1) to (0.5-1) to (0.5-1) to (1-3) to (2-4) to (4-6); composite plant composition powder is prepared from the six natural plant extracts through a series of separation and purification processes; and in addition, the composition microcapsule is obtained from the composite plant composition powder by a liposome embedding technology. The obtained composite plant composition microcapsule is good in stability, does not change the physical and chemical properties of cosmetics when applied to the cosmetics, is stable in color, has the effects of resisting allergy, relieving the skin, resisting inflammation, resisting irritation and relieving itching, is obvious and lasting in efficiency and has slow-release property.