The invention provides a bus intelligence operation method and a system. A pressure sensor at boarding and alighting door step can monitor a passenger load weight comprising a passenger weight and a carried article weight. Load detection in the bus is accurate so that an overload hazard caused by only number of people statistics is avoided and a bus operation safety factor is increased. Simultaneously, a passive infrared sensor is used to detect a human body height so that distinguishing of children and adults and a voice prompt of giving seat to children are realized. Through using giving seat calling button installed on a bus armrest, a voice prompt of giving seats to senior citizens, infirm people, patients, disabled people and pregnant women is realized. Consciousness of civilized giving seat of passengers is enhanced and civil bus ride in the bus is increased. An infrared range finding sensor is used to detect human body thickness. Through combining the human body thickness and the weight collected by the pressure sensor, accurate passenger flow volume monitoring and people counting are realized, which provides a basis for next bus operation optimization.