The effect of a treatment on a rock sample or sub-sample extracted from the rock sample can be analyzed through computed tomography (CT). To determine the effect of a treatment of a rock sample or the sub-sample, pre-treatment and post-treatment CT images of the rock sample or the sub-sample are captured. Further, the pre-treatment CT images and post-treatment CT images of the rock sample or the sub-sample are compared based on one or more alignment markers added to the rock sample or the sub-sample. In some embodiments, pre-treatment and post-treatment CT scans of an extracted sub-sample provide higher-resolution information regarding the effect of the treatment. Further, pre-treatment and post-treatment CT scans of a rock sample with a restored sub-sample may be considered and may provide additional information regarding the effect of the treatment on the rock sample or the sub-sample.