Disclosed is a method for predicting depth map coding distortion of a two-dimensional free viewpoint video, including: inputting sequences of texture maps and depth maps of two or more viewpoint stereoscopic videos; synthesizing a texture map of a first intermediate viewpoint of a current to-be-coded viewpoint and a first adjacent viewpoint, and synthesizing a texture map of a second intermediate viewpoint of the current to-be-coded viewpoint and a second adjacent viewpoint by using a view synthesis algorithm; recording a synthetic characteristic of each pixel according to the texture map and generating a distortion prediction weight; and calculating to obtain total distortion according to the synthetic characteristic and the distortion prediction weight.