The invention discloses a comprehensive utilization method of a magnetite-containing country rock. The method comprises the following steps: (1) performing a first-stage dry magnetic separation to obtain rough concentrate of the first-stage dry magnetic separation, and using thrown tailings of the first-stage dry magnetic separation as concrete aggregate; (2) performing a second-stage dry magnetic separation to obtain rough concentrate of the second-stage dry magnetic separation, and using the thrown tailings of the second-stage dry magnetic separation as the concrete aggregate; (3) performing high-pressure roller grinding-wet coarse grain magnetic separation; and (4) performing staged wet ore grinding and magnetic separation operation. According to the method, the iron-containing country rock with total iron grade about 13% and magnetic iron grade about 7% can be treated, the iron ore concentrate with yield about 8%, total iron grade not less than 63% and magnetic iron recovery rate not less than 80% can be obtained besides the concrete aggregate with the yield about 70% and the granularity of 50-0mm. The method has the advantages of energy saving, environmental protection, strong adaptability, and good economic benefit, and can be widely applied to the magnetite mine, and especially suitable for treating the magnetite country rock with low grade.