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发明授权
CN104640538B 包含NDGA 衍生物和索拉非尼的组合物以及其在治疗癌症中的用途 有权

包含NDGA 衍生物和索拉非尼的组合物以及其在治疗癌症中的用途
摘要：
本发明提供了包含包括M4N(四‑O‑甲基去甲二氢愈创木酸)的NDGA衍生物和索拉非尼的药物组合物，及其在抑制和治疗例如，在受试者中的肿瘤性疾病，诸如肝癌、结肠癌、乳腺癌、脑癌和卵巢癌中的用途。还提供了包含包括M4N的NDGA衍生物、索拉非尼和另外的治疗剂的组合物。
摘要（英）：

The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.

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