The invention discloses a solid-state drive encryption key generation method. The method includes: a user setting encryption key factors through a management procedure; the user setting solid-state drive registration information through the management procedure; a solid-state drive security module generating random numbers serving as encryption key random factors; the solid-state drive security module synthesizing encryption key factors, solid-state drive registration information and the random factors into the encryption key by a key synthesis algorithm. With the method, the solid-state encryption key factors, the solid-state drive registration information and the encryption key random factors are set by the user for associated disposal, the encryption key is synthesized, the problem that the user cannot participate in the encryption key generation process is effectively solved, strength of the encryption key is enhanced, and security of the encryption key is improved.