The invention discloses a traditional Chinese medicine preparation for treating chronic urticaria. The traditional Chinese medicine preparation comprises the following medicines by weight: 20-30g of rhizoma smilacis glabrae, 10-20g of lithospermum, 10-20g of herba schizonepetae, 10-20g of periostracum cicada, 10-20g of sesame seeds, 10-20g of akebiaquinata, 10-20g of burdocks, 10-20g of cortex dictamni, 10-20g of peach kernels, 8-15g of fructus kochiae, 8-12g of duckweeds, 8-12g of ephedra, 8-12g of polygonum multiflorum, 8-12g of flos carthami, 8-12g of stiff silkworms, 8-15g of radix scrophulariae, 8-15g of selfheal and 8-12g of dandelion. The medicines are precise to combine and reasonable to formulate, and play the roles of strengthening the spleen and stomach, benefiting qi for activating blood circulation, dispelling pathogenic wind and removing dampness, removing heat to cool blood and eliminating swelling and reliving itching together. The traditional Chinese medicine preparation for treating chronic urticaria has the advantages of being remarkable in curative effect, low in cost, free of side effects, high in cure rate, difficult to recur and the like an is worth clinically popularizing and applying.