The invention discloses a multifunctional pathologic sampling chopping board which comprises two side surface supporting frames, a chopping board and an instrument disinfecting box, wherein a chopping board supporting plate used for supporting the chopping board is arranged between the two side surface supporting frames, the chopping board is mounted above the chopping board supporting plate in a sliding manner and is jointed with the upper-edge surface of the chopping board supporting plate; the instrument disinfecting box is mounted between the two side surface supporting frames in a sliding manner and positioned below the chopping board supporting plate. The multifunctional pathologic sampling chopping board can be used for effectively solving the defect of an existing pathologic sampling chopping board, can fully adapt to demands of clinical pathology, autopsy and experimental animal sample drawing, and is used for remarkably improving the working quality and efficiency. In addition, the multifunctional pathologic sampling chopping board is simple in structure, and convenient to mount, use and manufacture.