The invention discloses a centralized relay protection device. The centralized relay protection device comprises far-end data collecting units, far-end motion executing units, a network switch unit and a centralized control unit. The far-end data collecting units are used for collecting information of an electric power system and transmitting the information to the centralized control unit through the network switch unit, the centralized control unit generates a motion set, and the motion set is issued to the far-end motion executing units through the network switch unit. Control devices are deployed in a centralized mode, collecting and motion devices are deployed in a dispersed mode, and based on synthesizing positions of all the collecting and motion devices in electric power topology and historical operation data information of a whole net, the optimal motion behavior is done through decision making conveniently; an electric power topology network and a relay protective motion strategy can be configured on the centralized control devices flexibly, and the maintainability and the expandability of the system are improved.