The invention provides an integrated anti-disengaging wrench. The integrated anti-disengaging wrench comprises a wrench body, an anti-disengaging part and a pushing device. A mounting groove is formed in the upper end face of the wrench body, the mounting groove extends to a connecting hole of the wrench body, and the two side walls of the mounting groove extend inwards to form two groove top clamping faces. The anti-disengaging part is arranged in the mounting groove of the wrench body. The pushing device is fixedly connected with one end of the anti-disengaging part, and is used for horizontally pushing the anti-disengaging part out of the mounting groove to enable the anti-disengaging part to extend to the connecting hole of the wrench body. The mode of two anti-disengaging rods is used for preventing nuts and the connecting hole of the wrench body from being disengaged, and meanwhile rod bodies of screw rods are made to penetrate through the gap between the two anti-disengaging rods. Accordingly, the integrated anti-disengaging wrench is particularly suitable for the circumstance of two nuts, and the two anti-disengaging rods can assist the nuts to achieve disengaging prevention without affecting the rod bodies of the screw rods.