The invention discloses a nematic-phase liquid crystal composition which is formed by two components. The first component comprises one or more chemicals in a structural formula I, and the second component comprises one or more chemicals in a structural formula II and one or more chemicals in a structural formula III. The liquid crystal composition is excellent in performance, has a wide nematic-phase temperature range, proper positive dielectric anisotropism, proper optical anisotropism, high charge retention rate, high response speed and low rotary viscosity and can maintain high charge retention rate. The composition has a wide application prospect and application value in liquid crystal display and is especially suitable for manufacturing active matrix IPS-TFT displayers with a high response speed.