The invention discloses a high-voltage plug-in structure of a quickly-change battery pack for an electric automobile. The high-voltage plug-in structure of the quickly-change battery pack for the electric automobile comprises a high-voltage plug-in part, wherein the high-voltage plug-in part comprises two conductive core parts, the end part of each conductive core part is provided with a guiding circular bead for guiding a mating end inserted with the high-voltage plug-in part. According to the high-voltage plug-in structure of the quickly-change battery pack for the electric automobile, when limited position deviation is caused in contact of the high-voltage plug-in part with the mating end, the high-voltage plug-in part and the mating end are assembled due to the guiding action of the guiding circular bead of the conductive core part, thus, the assembling operation is smooth, the battery can be frequently replaced conveniently and the life of the plug-in part is ensured in the future quickly-change operations, the quickly-change efficiency can be improved, good high-voltage loop performance is kept, the faults are reduced and the potential safety hazard is avoided; and besides, the contact core part is kept to be in an original free state position and the position consistency is ensured after the high-voltage plug-in part is connected with the adjacent electric device.