The invention discloses a disperse blue dye composition. The composition is basically prepared from one or more of a component A as shown in a formula (I), a component B as shown in a formula (II) and a component C as shown in a formula (III). Furthermore, a component D as shown in a formula (IV) and a component E as shown in a formula (V) can be selectively added into the disperse blue dye according to requirements. The invention further discloses a preparation method and an application of the composition. The disperse blue dye has the advantages of bright color, good sublimation fastness, good perspiration fastness, good light fastness and the like, the dye cost is relatively low, and pollution is relatively small.