The invention relates to the technical field of building structures, and in particular relates to a masonry structure with plant stems and a manufacturing method thereof. The masonry structure with the plant stems comprises a building block, a ground ring beam, a left constructional column, a right constructional column and a top ring beam. Compared with a wall body without stems in the prior art, the rigidity, the bearing capacity, the ductility and the energy consumption of the masonry structure with the plant stems disclosed by the invention are increased to a large extent; the bearing capacity, the durability, the ductility, the rigidity and the energy consumption required by the wall body are ensured; the anti-seismic property of the integral body is increased; the comprehensive cost of the masonry structure with the plant stems disclosed by the invention is lower than that of a wall body completely with stems, a brick-concrete structure, a frame structure and a steel structure in the prior art; simultaneously, the plant stems can be cotton straws, branches, bamboos or crop straws; therefore, atmospheric pollution caused by straw incineration is reduced; straws in local can be sufficiently utilized; thus, the utilization rate of the straws is greatly increased; and the building cost of farmers is reduced.