The invention relates to a secure access method applicable to enterprise-level mobile applications. The method includes the implementation steps of (1) network access permission, (2) device legality verification, (3) user legality verification and (4) user access right control. By implementation of the secure access method applicable to the enterprise-level mobile applications, mobile application intrusion means such as identity forging, man-in-the-middle hostage, information interception, replay attack and information tampering are effectively prevented, illegal devices, individuals or applications are effectively blocked from accessing to enterprise networks, and secure and effective access to the enterprise mobile applications is guaranteed.