The invention provides a sickbed drive control method and device. The method comprises the following steps: determining a threshold of a drive parameter according to the weight of a patient; under the situation that a drive parameter value of a sickbed is smaller than the threshold of the drive parameter, driving the sickbed along a first direction by taking a preset value of the drive parameter as an initial drive parameter value; when the deviation of a moving trajectory of the sickbed from a preset trajectory corresponding to the preset value exceeds a preset range, driving the sickbed along a second direction, wherein the second direction is opposite to the first direction. Through the method and the device, body injuries can be prevented from being caused to the patient during the movement of the sickbed.