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发明公开
CN104059993A 特异性结合DOCK8基因片段的探针、检测DOCK8突变情况的试剂盒及方法 有权

特异性结合DOCK8基因片段的探针、检测DOCK8突变情况的试剂盒及方法
摘要：
本发明涉及基因片段突变检测领域，特别涉及特异性结合DOCK8基因片段的探针、检测DOCK8突变情况的试剂盒及方法。该特异性结合DOCK8基因片段的探针的序列如SEQ ID NO：1所示。本发明提供的特异性结合DOCK8基因片段的探针能够特异性结合DOCK8基因片段；本发明提供的检测方法能够准确检测DOCK8基因有无突变情况，并对突变进行准确定位。该方法不仅能筛查点突变，还能准确检测大片段缺失突变，操作简单，耗时短，外显子捕获率可达100％。
摘要（英）：

The invention relates to the field of detecting the mutation of a gene segment, and particularly relates to a probe specifically combined with a DOCK8 gene segment, and a kit and a method for detecting the mutation status of DOCK8. The sequence of the probe specifically combined with the DOCK8 gene segment is shown as SEQ ID NO:1. The probe can be specifically combined with the DOCK8 gene segment; through using the detection method, whether the DOCK8 gene has mutation status can be accurately detected, and the mutation can be precisely located. The method not only can screen point mutation, but also can detect the missing and mutation of large segments, and is simple to operate, and short in consumption time, and the capture rate of exon can achieve 100%.

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