The invention discloses a venous transfusion device with a driving plate type flow regulation device. The venous transfusion device comprises a transfusion plug, an intake tube, a Murphy's drip cup, an infusion tube, the driving plate type flow regulation device, a filter and a venous infusion needle, and is characterized in that the driving plate type flow regulation device is arranged between the Murphy's drip cup and the filter; the driving plate type flow regulation device comprises an upper cover, a seal ring, a lower cover and a driving plate; the driving plate is located between the upper cover and the lower cover; a cylinder at the lower part of the driving plate is inserted in a blind hole of the lower cover; the driving plate can rotate around a center shaft of the cylinder, so as to change the superposed area between a crescent-shaped through hole slot in the middle of the driving plate and an upper cover hole. The venous transfusion device can regulate transfusion flow and is accurate in regulation, simple in structure, and convenient to operate.